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Substance |
Bicalutamide |
---|---|
Brand name: |
Casodex |
Description |
|
Hormone associated therapy and hormone based chemotherapy |
|
Casodex is prescribed to patients, diagnosed with hirsutism |
|
Brands: |
Casodex |
Availability: |
Prescription needed |
Pregnancy: |
Consult a doctor |
Alcohol: |
The drug deteriorates its properties when used with alcohol |
Side Effects: |
Abnormal growth filled with fluid or semisolid material |
Interactions: |
Simvastatin |
Casodex dose
Casodex (biclutamide) is an anti-androgen type of hormone therapy used to treat prostate cancer that has metastasized (spread to other parts of the body. The area under the plasma concentration-time curve increased linearly with dose, and Casodex was eliminated slowly from plasma (t1/2 about 6 days) Casodex is a potent and specific non-steroidal antiandrogen. Clinical studies indicated that Casodex is orally bioavailable and well absorbed, with a plasma half-life of around 1 week. Objective assessments of efficacy included: review of measurable metastases, prostate dimension, prostatic acid phosphatase and prostate-specific antigen (PSA) levels. Off-label use in the treatment of locally advanced Prostate cancer including those at a high risk of recurrence. Steady state plasma concentrations of the (R)-enantiomer of approximately 9 microgram/ml are observed during daily administration of 50 mg doses of Casodex The doses ranged from 10 to 200 mg. Treatment with CASODEX should be started at the same time as treatment with an LHRH analog Use effective birth control to prevent pregnancy while using Casodex and for at least 130 days (about 19 weeks) after your last dose. The tablets should be swallowed whole with liquid and can be taken with food. 150 mg orally once a day as monotherapy. Subjective assessments of efficacy included review of urological symptoms, performance status, bone scan and analgesic requirement Bicalutamide (casodex) Dose in Adults Bicalutamide (casodex) in the treatment of metastatic Prostate cancer: 50 mg orally once a day in combination with an LHRH analog. Effectiveness A clinical study found Casodex to be as effective as a drug called. Recommended Dose and Schedule The recommended dose for CASODEX therapy in combination with an LHRH analog is one 50 mg tablet once daily (morning or evening), with or without food. Treatment with CASODEX should be started at the same time as treatment with an LHRH analog Casodex comes as tablets that you take by mouth once a day. Testosterone can stimulate the growth of prostate cancer cells Recommended Dose And Schedule The recommended dose for CASODEX therapy in combination with an LHRH analog is one 50 mg tablet once daily (morning or evening), with or without food. ) is just as effective as flutamide + leuprolide. On daily administration of Casodex, the (R)-enantiomer accumulates about 10 fold in plasma as a consequence of its long half-life. It is recommended that CASODEX be taken at the same time each day. If a moderate CYP3A inhibitor must be used, reduce the venetoclax dose by at least 50%. Try to take your medication at about the same time each day. Bicalutamide/Casodex Oral Tab: 50mg DOSAGE & INDICATIONS For the treatment of prostate cancer. Monitor more closely for signs of venetoclax toxicities An antiandrogen therapy, Casodex is given in combination with another medication called a luteinizing hormone-release hormone (LHRH) agonist. [10] It is typically used together with a gonadotropin-releasing hormone (GnRH) analogue or surgical removal of the testicles to treat advanced prostate cancer.. 1 It works by blocking testosterone, a male sex hormone that is also known as an androgen, from binding to androgen receptors. A Casodex dose of 50 mg daily decreased prostatic acid phosphatase comparable with castration The usual dose is one tablet a day. The doses ranged from 10 to 200 mg. They are available only in one strength: 50 mg. Casodex displays prolonged absorption following a single dose, with peak plasma concentrations observed at up to 8 h for doses of 10 mg and 30 mg. Call your doctor at once if you have nausea, upper stomach pain, itching, loss of appetite, dark urine, clay-colored stools, or jaundice (yellowing of the skin or eyes) bicalutamide will increase the level or effect of venetoclax by affecting hepatic/intestinal enzyme CYP3A4 metabolism. [10] It is typically used together with a gonadotropin-releasing hormone (GnRH) analogue or surgical removal of the testicles to treat advanced prostate cancer Official answer. A clinical study for Stage D2 Prostate Carcinoma comparing leuprolide with leuprolide + flutamide showed:. For the treatment of stage D2 metastatic prostate cancer, in combination with a luteinizing hormone-releasing hormone (LHRH) analog. Bicalutamide Bicalutamide, sold under the brand name Casodex among others, is an antiandrogen medication that is primarily used to treat prostate cancer. Do not stop taking your medicine, even if you feel well unless you are immediately told by your doctor to stop.
Cost for casodex
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